Leiden University Medical Center
The Leiden University Medical Center (LUMC) is a modern university medical center for research, education and patient care with a high quality profile and a strong scientific orientation. The department of Clinical Pharmacy and Toxicology (hospital pharmacy) takes care of and guarantees an effective, save and efficient treatment with drugs for the patients of the LUMC. The department has a strong research record with a predominant focus on personalized medicine. As drug response is highly variable based on individual patient characteristics and genetics it is of importance to improve our ability to personalize one’s drug treatment based on these inter-individual differences. To achieve these research ambitions we have formed a group of experts that covers the required fields within the area of clinical pharmacology, pharmacogenomics, human genetics, pharmacokinetics, pharmacodynamics, pharmacometrics, bio-informatics and bio-analytics and collaborate with many national and international groups.
Role within SafePolyMed
The LUMC leads SafePolyMed's WP5 "Clinical Case Study". In this role, LUMC will coordinate the multi-center clinical study “Empowering Patient to Improve Safety in Polymedication” (EmPaSafe), which aims at evaluating the feasibility of the Medication Management Center (MMC) and its content as developed in other WPs. To this end, polypharmacy patients in different healthcare settings (e.g. primary care, psychiatry, geriatric) will be recruited. Secondary to the feasibility, LUMC will collect data on adverse drug reactions (ADRs), pharmacogenetics and other patient characteristics to assess if the MMC can help prevent ADRs in the polypharmacy population.
